Current Clinical Research Activities








1. Sponsor: Orthovita
A Randomized, Controlled Clinical Study to Evaluate the Safety and Effectiveness of
Cortoss® Synthetic Cortical Bone Void Filler in Vertebral Augmentation

2. Sponsor: Advanced Bionics and Millennium Pain Center
Spinal Neuromodulation in the Treatment of Chronic Discogenic Low Back Pain

3. Sponsor: Advanced Bionics and Millennium Pain Center
Paresthesia and Spinal Cord Stimulation: Functional Relevance or Sensory Overlap?

4. Sponsor: Advanced Neuromodulation Systems (A St. Jude Medical Co.)
A Clinical Evaluation of the Eon™ 16-Channel Implantable Pulse Generator (IPG) in
combination with two Octrode® (8 contact) leads for the management of chronic back pain
with or without neuropathic leg pain

5.   Sponsor: Medtronic
Implantable System Performance Registry (ISPR)

6.  Sponsor: Covance/Sucampo
A Multicenter, Randomized, Placebo-controlled, Doubleblinded Study of  the Efficacy and
Safety of Lubiprostone in Patients with Opioid-induced  Bowel Dysfunction

7.  Sponsor: Covance/Sucampo
A Multi-Center, Open-Labeled Study of the Long-Term Safety and Efficacy of Lubiprostone
in Patients with Opioid-Induced Bowl Dysfunction

8.   Sponsor: Nektar/Parexel
A Phase 2, Double-Blind, Randomized, Placebo-Controlled, Multiple-Dose, Dose Escalation
Study to Evaluate the Efficacy, Safety and Tolerability of NKTR-118 in Patients with Opioid-
Induced Constipation (OIC)

9.   Sponsor: Alquest/EMPI
The E-STIM Trial:  A Randomized, Double-Blind, Multicenter Trial Comparing the Efficacy
of theEmpi SelectTM Transcutaneous Electrical Nerve Stimulation (TENS) to a Control for
the Treatment of Chronic Lower Back Pain

10.  Sponsor: Omnicare/Johnson and Johnson
A Randomized, Double Blind, Placebo- and Oxycodone Immediate Release (IR)-Controlled
Study of Tapentadol HCl IR for the Treatment of Acute Pain Caused by Vertebral
Compression Fractures Associated with Osteoporosis